Amyloidosis
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Summary
Amyloidosis occurs when abnormal proteins called amyloids build up and form deposits. The deposits can collect in organs such as the kidney and heart. This can cause the organs to become stiff and unable to work the way they should.
There are three main types of amyloidosis:
- Primary - with no known cause
- Secondary - caused by another disease, including some types of cancer
- Familial - passed down through genes
Symptoms can vary, depending upon which organs are affected. Treatment depends on the type of amyloidosis you have. The goal is to help with symptoms and limit the production of proteins. If another disease is the cause, it needs to be treated.
- Amyloidosis (American Society of Clinical Oncology)
- Amyloidosis (Mayo Foundation for Medical Education and Research)
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Amyloidosis and Kidney Disease
(National Institute of Diabetes and Digestive and Kidney Diseases)
Diagnosis and Tests
- Bone Marrow Aspiration and Biopsy (American Association for Clinical Chemistry)
- Serum Free Light Chains (American Association for Clinical Chemistry)
- Urine Protein and Urine Protein to Creatinine Ratio (American Association for Clinical Chemistry)
Related Issues
- AL Amyloidosis and Agent Orange (Department of Veterans Affairs)
-
General Information about Plasma Cell Neoplasms (Including Multiple Myeloma)
(National Cancer Institute)
Also in Spanish
Specifics
- Cardiac Amyloidosis (American Heart Association)
Genetics
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Genetics Home Reference: hereditary cerebral amyloid angiopathy
(National Library of Medicine)
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Genetics Home Reference: lattice corneal dystrophy type II
(National Library of Medicine)
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Genetics Home Reference: primary localized cutaneous amyloidosis
(National Library of Medicine)
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Genetics Home Reference: transthyretin amyloidosis
(National Library of Medicine)
Clinical Trials
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ClinicalTrials.gov: Amyloidosis
(National Institutes of Health)
Journal Articles References and abstracts from MEDLINE/PubMed (National Library of Medicine)
- Article: Pleural amyloidosis with recurrent pleural effusion and pulmonary embolism: A...
- Article: Patisiran for the treatment of hereditary transthyretin-mediated amyloidosis.
- Article: Complete remission of both immunoglobulin light chain amyloidosis and psoriasis...
- Amyloidosis -- see more articles
Patient Handouts
- Cardiac amyloidosis (Medical Encyclopedia) Also in Spanish
- Hereditary amyloidosis (Medical Encyclopedia) Also in Spanish
- Primary amyloidosis (Medical Encyclopedia) Also in Spanish
- Secondary systemic amyloidosis (Medical Encyclopedia) Also in Spanish